Friday, December 10, 2021

Lupine Publishers| Right Versus Left-Sided Colon Cancer: Analysis of Epidemiology in Lebanese Patients

 

  Lupine Publishers | Journal of Health Research and Reviews

Abstract

Objective: Recent studies have showed that right-sided colon cancer was more aggressive than left-sided and was more common in female and older patients. We examined the incidence of colon cancer by location (right versus left sided) in one university medical center, located in Beirut, Lebanon.

Methods: We collected the data of patients with colon cancer diagnosed between the years of 2011 and 2016 in Geitawi University Hospital, comparing the epidemiology of cases with right versus left sided colon cancer; concerning the following variables: age, sex, RAS status and the stage according to the American Joint Commission of Cancer AJCC.

Results: 96 patients were included, 61% had left-sided, 36% had right-sided, 1.5% had cancer in the transverse colon and 1.5% had synchronous left and right sided colon cancer. Patients with transverse and both right and left sided colon cancer were excluded from the study. We examined the incidence in patients under the age of 50; in whom screening is not recommended, versus patients over the age of 50; in whom screening is recommended. Patients with left-sided colon cancer were more common, more likely to be younger, to be males and to be diagnosed with a more advanced stage. In patients under the age of 50, 20% had cancer in the right and 80% had left-sided colon cancer.

Conclusion: Patients with right-sided were less common, predominantly males, older and with less aggressive stage than patients with left-sided colon cancer in a sub-group of Lebanese population.

Keywords: Colon Cancer; Right Sided; Left Sided; Epidemiology

Introduction

Colorectal cancer is one of the most commonly diagnosed cancers worldwide with over 1.2 million new cases and 608,700 deaths estimated to occur annually [1]. Colorectal cancer (CRC) is the second leading cause ofcancer-related deaths for both men and women in the United States, with 147,000 new occurrences and 50,000 deaths in 2009 [2]. Over the past years, the distinction between right-sided and left-sided colon cancer has been brought into consideration, regarding epidemiology, clinical presentation, pathology, and genetic mutations [3] Bufill in 1990 was the first to propose this, knowing that there are a number of differences between the sides of the bowel, for example the embryological beginnings; with the right bowel arising from the midgut and the left side from the hindgut, in addition to the difference in the vascular supply of each side [4].Epidemiological studies have demonstrated a gender and age relationship with a higher incidence of right colon cancer (RCC) in women and elderly people. Therefore, it has been suggested to consider colo-rectal cancer as three distinct tumor entities: right colon cancer (RCC), left colon cancer (LCC) and rectal cancer [5]. Right-sided colon cancers tend to be bulky, exophytic, polypoid lesions growing into the colon lumen and causing anemia. However, left-sided colon cancers tend to be infiltrating, constricting lesions en-circling the colorectal lumen and causing obstruction [6]. The idea of personalized medicine was introduced to the treatment of metastatic colorectal cancer (mCRC) when KRAS codon 12/13 mutations were identified as negative predictors of anti-EGFR-antibody (EGFR-mAB) treatment [7]. While there are many publications worldwide regarding this difference, it’s the first time in Lebanon we approach this issue. We studied patients with colon cancer admitted to Geitawi University Medical Center in an interval of 6 years (Figure 1).

Figure 1: The different entity of colon cancer Right Colon (ascending colon + hepatic flexure) Transverse Colon Left Colon (splenic flexure + descending colon + sigmoid).

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Methods

Data selection

The data was detected from the archive of data base in Geitawi University Medical Center in Beirut. Patients selected were those diagnosed with colon cancer between the year of 2011 and 2016. The data selected included: patients age, tumor location, tumor stage and RAS status in stage 4 colon cancer.

Patient selection

All patients who were diagnosed with primary adenocarcinoma of the colon in Geitawi hospital from 2011 to 2016 were included in the study,96 patients were identified, 22 patients were excluded either because the location of the cancer was not exactly identified or because the workup and management was continued outside the hospital, also 2 patients were excluded because the Cancer was located in the transverse or synchronous side right and left colon. Inclusion criteria were as follows:

a) All patients diagnosed with colon cancer between 2011 and 2016

Exclusion criteria were as follows:

b) Transverse colon cancer

c) Synchronous left and right sided colon cancer

d) Patients continued the care out of the hospital

e) Patient without exactly primary location of colon cancer

Figure 2: Data collection and sidedness of colon cancer

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After considering the above criteria, the patient pool consisted of 72 patients. They were distributed into two groups according to the colonic tumor site: 45 cases were found to be LCC and 27 were RCC. We collected the information considering the age, sex, stage according to AJCC American Joint Committee on Cancer and RAS status because Ras mutation was identified as a negative predictor of anti-EGFR-antibody (EGFR-mAB) treatment in each group. Then we divided the patients according to the age into two groups, one included patients < 50 years of age and the other included patients≥ 50 years (Figure 2).

Result

Out of the 72 patients, two thirds 62.5% had LCC, 37.7% were right-sided, 57% were males, 43.5% were females, and the mean age of the patients upon diagnoses was 65 years (Table1). In the Left-sided subgroup, the mean age was 62.5 years, 53% were males, 47% were females, and according to the AJCC staging system; 49% had tumor with stage 4 upon presentation and 51% had tumor with stage less than 4.The RAS status was found to be wild in 30% and mutated in 61% of cases, knowing that the mutation was not done in 9% of patients.In the right-sided subgroup, the mean age was 68 years, 63% were males and 37% were females. Moreover, according to the AJCC staging system, 37% had stage 4 tumor upon presentation and 63% had tumor with stage less than 4. The RAS was wild in 20% and mutated in 30% of patients. The mutation was not tested in 50% of patients, of whom 75% did not test because they decided to receive palliative treatment only. With respect to the two groups divided according to age <50 and ≥50 years (Table 2), 13.9% of the total number of patients were under the age of 50. In the latter subgroup, 80% had LCC, 40% were males, 60% were females, and the mean age was 41 years. Moreover 40% were with stage 4 tumor and 60% had tumor with stage < 4 upon diagnosis. Regarding the subgroup including patients ≥ 50 years, 59.7% LCC, 59.7% were males and 40.3% were females. The mean age was 69 years, 46.8% were with stage 4 tumor and 53.2% had tumor in stage < 4 upon diagnosis (Figure 3) (Tables 1-2).

Figure 3: Epidemiologic differences between the 2-age group.

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Table 1: Epidemiologic differences between right-sided and left-sided colon cancer.

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Table 2: Epidemiologic differences between the 2-age group.

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With respect to patients with right-sided colon cancer, 2 patients had stage 4 tumor with wild type RAS, both treated with EGFR targeted therapy. One patient passed away after progression in his disease status and the other one didn’t respond to first line treatment.

Discussion

Patients with RCC were, overall, older, more often of female gender, and had more advanced AJCC stages than patients with LCC [1]. Differences in clinical presentation, epidemiology, and tumor biology between right and left-sided colon cancer have long been reported in the literature [2-6]. This study retrospectively collected the data from the archive of Geitawi University Medical Center and showed that patients with LCC were more often of female gender and had more advanced AJCC stages than patients with RCC. There were more patients <50 years with LCC than with RCC, and the progression of the tumor was less aggressive compared to patients≥ 50 years. Our study showed that RCC is less aggressive than LCC and this result, despite the small number of patients included in our study, is in contradiction with the results published in the studies mentioned above, which may let us question the role of ethnicity and geographic factors in this issue. Thus, additional studies should be done to confirm this hypothesis. The retrospective analysis of RAS mutation status in patients with colon cancer of stage 4 showed that RAS was mutated in patients with LCC more than those with RCC. The last study of CALGB/SWOG 80405 (Alliance) showed that patients who received cetuximab and had left-sided tumor had a median overall survival (OS) of 36 months versus 16.7 months for patients with right-sided tumor. While patients who received bevacizumab had an overall survival of 31.4 months for those with left-sided tumor versus 24.2 months for those with right-sided tumor [8,9]. These findings played a role in changing the guidelines by limiting the use of cetuximab to patients with LCC only. Also, in our study 2 patients with RCC RAS wild type were treated with EGFR targeted therapy and both demonstrated progressive disease. These data concur with the above study and may lead us to restrict ordering RAS mutation studies to patients with RCC only, perhaps reducing the financial burden. Our study’s limitations were the small number of patients included with data collected from only one center, and it didn’t report overall survival or progression free survival.

Conclusion

The patients with right-sided colon cancer were more commonly males, older and had less aggressive tumor than patients with left-sided colon cancer, contrasting with the studies published internationally. Moreover, patients under the age of 50 were more often females, had LCC more than RCC, and the progression of the tumor was less aggressive than in patients above the age of 50 years.

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Monday, December 6, 2021

Thursday, December 2, 2021

Tuesday, November 23, 2021

Monday, November 22, 2021

Lupine Publishers| Impact and Challenges of Electronic Services and Devices on Medical Laboratory Practice; A Study in the Central Region of Ghana

 

  Lupine Publishers | Journal of Health Research and Reviews

 

Abstract

Background: The introduction of electronic services and devices has led to rapid and dramatic innovation and development in the laboratory environment. However, despite the numerous achievements and contributions in the health sector, laboratory practice continues to encounter certain difficulties in the use of electronic services and devices.

Objective: This study examined the challenges medical laboratory personnel face in the use of electronic services and devices, and its impact on the attitude of medical laboratory personnel.

Methods: A total of 62 medical laboratory personnel were conveniently selected from 8 hospitals within the Central region of Ghana. A questionnaire on Electronic Medical Laboratory Personnel Services for Efficient Health Delivery Services in Ghana was used to collect data for the study. Data collected were screened, coded and entered into computer software, and analysed using the Statistical Package for Social Sciences (SPSS version 21) for Windows.

Results: Findings revealed that the supply of electronic device accessories such as reagent was a challenge as only 37.1% of the respondents agreed it was easy. About 15% responded that maintenance/servicing of electronic device was easy. Majority showed positive attitude towards the operation of electronic device understanding principle under which electronic devices work. A higher proportion of the respondents agreed to the fact that results produced by electronic device are reliable, with average duration of producing being minutes indicating a better turnaround time. The use of electronic services and devices in the medical laboratory has had a positive impact on the attitude of some medical laboratory personnel.

Conclusion: Maintenance and repair works on electronic devices by maintenance/service team have to be prompt and regular. Workshops and training should be organized on use of electronic services and devices on regular basis for medical laboratory personnel so they could be abreast with current trends in their usage.

Keywords: Electronic Services and Devices; Laboratory, Medical Laboratory Personnel

The use of medical laboratory tests to detect, diagnose, monitor and treat disease keeps on increasing day by day. The results produced by medical laboratory tests are used by physicians to make decisions regarding a patient’s medical condition. Some sources estimate that 70-80% of decisions made by physicians are directly dependent on medical laboratory values [1]. According to contribution to modern medicine by laboratories has been recognized as something more than the addition of another resource to medical science and is now being regarded as the seat of modern medicine, where physicians account for what they observe in their patients. As stated by [2], the emergence of sophisticated automated laboratory machines with complex procedures and the laboratories that housed them coincided with the worldwide political, industrial and philosophical revolutions. These have transformed our world which was dominated by religion and aristocracy into those dominated by the industrial, commercial and professional classes. Years after years, laboratories and their heads were met with opposition especially those clinicians who did not understand their work and saw their profession as a threat to science. However, as they continuously practice this profession, lay people and many health practitioners saw the introduction of medicine in the laboratory as a removal of medical knowledge from the realm of common experience to that of evidence based. Recently, with the introduction of electronic services and devices, the laboratory environment has experienced rapid and dramatic innovation and development [1]. There has been a significant increase in the variety and nature of medical laboratory investigations and services. This is due to technology and it is expected to continue. This has made laboratory technology according to [1] the forefront of medical advances. Testing techniques to diagnose or screen for a particular condition are now available before effective treatment. According to [3], advance in medical laboratory technology involving new tests, automated equipment and testing technique has resulted in a more efficient laboratory testing [4]. As stated by [5], information technology has also influenced the transfer of data by decreasing the time it takes to request for and receive test results and also by creating opportunities for research on large datasets. The integration of electronic services into medical laboratory practice may be affected by policies related to training of personnel, attitude of personnel, coverage and finally payment of services. Ghana was celebrated in 2013 for hosting five out of the nine state owned ISO laboratories in West Africa. Besides these ISO laboratories, there are numerous laboratories spread along the length and breadth of the country which function in hospitals, clinics just like strategically positioned private laboratories [6]. All these achievements are through the efforts of the scientists and the introduction of modern technology. However, despite the numerous achievements and contributions in the health sector in disease diagnosis, prevention, managements and prognosis, laboratory practice continues to encounter certain difficulties in the use of electronic services and devices. Therefore, this study examined the challenges medical laboratory personnel face in the use of electronic services and device and its impact on the attitude of medical laboratory personnel in the Central Region of Ghana.

Research Design and Site

A cross-sectional study with quantitative approach was conducted in the Central Region of Ghana. The Central Region is one of the ten administrative regions of Ghana. It is renowned for its many elite higher education institutions and an economy based on an abundance of tourist sites. There are seventeen districts in the region with each district having a health directorate and a district hospital and many health centers. There are also some mission and private hospitals in the region. The region has a regional hospital and a teaching hospital which attend to referral cases from the district hospitals and other health facilities. All these health facilities have medical laboratories which are in full operation with different categories of medical laboratory personnel performing various functions. The district, municipal, teaching, mission and some private hospitals have laboratories which make use of electronic services and devices in the running of patient sample. The laboratories included Cape Coast teaching hospital, Winneba and Swedru Municipal Hospitals and Kasoa District Hospital. The mission and private laboratories selected were Apam Catholic Hospital, St. Joos Hospital, MDS Lancet and Sanford Hospital.

Population

The target population for this study was all medical laboratory personnel in the central region who make use of electronic services and devices in their daily practice.

Sampling Procedure

Convenience sampling method was used to choose the sample. Convenience sampling according to Dörnyei (2007), is a type of non-probability or non-random sampling where members of the target population that meet certain practical criteria such as easy accessibility, geographical proximity, availability at a given time, or the willingness to participate are included for the purpose of the study. The researcher adapted convenience sampling method for this study because it was assumed that most of the staff from these laboratories either had a degree or an HND and were licensed and certified by the Allied Health Council of Ghana to use electronic services and devices. It was also assumed that personnel were also easy to reach and were readily available. It was assumed that convenience method placed primary emphasis on generalizability, thus ensuring that the knowledge gained was representative of the population from which the sample was drawn.

Sample Size

In this study, a sample of 62 medical laboratory personnel were conveniently selected from Cape Coast Teaching Hospital, Winneba and Swedru Municipal Hospitals, Kasoa District Hospital, Apam Catholic Hospital, St. Joos Hospital, MDS Lancet and Sanford Hospital. Out of the 62 laboratory personnel that were sampled, 6 came from medical laboratories in the teaching hospital, 14 from laboratories in municipal hospitals, 13 from district hospital laboratories, 14 from mission hospital laboratories and the remaining 15 from private medical laboratories. These laboratories were used because it was observed that they have the highest number of laboratory personnel who use electronic services and devices in the region.

Research Instrument

A questionnaire on Electronic Medical Laboratory Personnel Services for Efficient Health Delivery Services in Ghana was used to collect data for the study. A questionnaire: Electronic Medical Laboratory Personnel Services for Efficient Health Delivery Services in Ghana (Appendix A) was developed by the researcher based on extensive literature review on areas related to medical laboratory practice and electronic services. These areas included challenges medical laboratory personnel face in the use of electronic services and devices in the laboratory, impact of electronic services on the attitude of laboratory personnel, some unique skill that must be acquired in using electronic devices in the laboratory and finally measures to be put in place to ensure effective use of electronic services in the laboratory. A pool of 39 items was created using the content of areas reviewed as a guide. The items consisted of both positive and negative statements to avoid respondents’ answers being skewed toward the positive respond’s options. The questionnaire had open and close ended items.

Pilot Test

In this study, Electronic Medical Laboratory Personnel Services for Efficient Health Delivery Services in Ghana instrument was piloted with 5 medical laboratory personnel from the Baptist Hospital in Winneba to validate the effectiveness of the instrument, and the value of the questions to elicit the right information to answer the primary research questions. This preceded the main observation to correct any problems with the instrumentation or other elements in the data collection technique.

Validity of Instrument

Face validity of the questionnaire items for this study was determined by both Lecturers and colleague students to ensure there were no redundant and ambiguous items. All reviewers’ comments and suggestions were collected, analysed and considered. The final draft instrument contained four parts. The first part sought information on personnel biological and educational characteristics such as gender and age. The second and third part of the questionnaire sought information on some of the challenge’s medical laboratory personnel face in the use of electronic devices in the laboratory and the impact of electronic services on the attitude of laboratory personnel. The final part sought to identify some of the unique skill that must be acquired in using electronic devices in the laboratory and to find some of the measures to be put in place to ensure effective use of electronic services and devices in the laboratory.

Reliability of Instruments

Data from the pilot test was used to determine the reliability of research questionnaire. Item analysis was at the point carried out to identify items whose removal would enhance the internal consistency of the instrument.

Data Collection Procedure

Ethical approval was obtained from the Kwame Nkrumah University of Science and Technology (KNUST) ethical committee to medical laboratories whose personnel were part of the target population. The structured questionnaire was administered on the medical laboratory personnel at different times when they were working. The laboratories accessed included Cape Coast Regional and Teaching Hospital, Winneba and Swedru Municipal Hospitals and Kasoa District Hospital. The mission and private laboratories were Apam Catholic Hospital, St. Joos Hospital, MDS Lancet and Sanford Hospital. All the personnel who used electronic services and devices in these laboratories were eligible to participate in the study, but only those who gave their consents constituted the sample. The respondents were briefed on the intended research and their confidentiality assured as their names were not required. The questionnaire was then administered on the personnel from the selected laboratories.

Data Analysis

Data collected were screened, coded and entered into computer software. The analysis was done using the Statistical Package for Social Sciences (SPSS version 21) for Windows. Using this software, descriptive statistics function was used to determine the mean scores and standard deviations. These responses were converted into percentages for easy understanding and interpretation.

Table 1 shows the general characteristics of study participants. Most of the respondents were males (61%) with 39% females. The dominant age group was 20-30 years (54.8%) followed by age group of 31-40 years (33.9%). Six of the respondents representing 9.7% work in the Teaching hospital, 14(22.6%) work in Municipal hospital with 13 (21%) of respondents working in District hospital. Most (66%) of the respondents were medical laboratory scientist thus degree holders with only one (2%) of the respondents being a laboratory assistant thus certificate holder. Also, 13 (21%) were technicians (diploma holders), and 7 (11%) had other qualifications. Table 2 shows the mean scores of responses for challenges personnel face. Majority (66.1%) of the respondents showed positive attitude towards the operation of electronic device as less challenging (M=2.6613, SD=0.47713). The table also revealed that 48.4% (30) of the respondents had positive attitude towards understanding principle under which electronic devices work (M=2.4839, SD=0.50382). However, the supply of electronic device accessories such as reagent was observed to be a challenge and only 37.1% (23) of the respondents agreed that it was easy. A little over a quarter 27.4% (17) of the respondents out of the total number of respondents agreed that calibration of electronic device was easy, and therefore revealed negative response. Less than a quarter 14.5% (9) of the respondents out of the total number of respondents agreed that maintenance/servicing of electronic device was easy. This indicate that a significant number of the respondents have challenges in using electronic device when there is the need to either maintain or service them. With the documentation of result by electronic equipment as a challenge, most of the respondents, 71% (44) of the sample scored 3 with a mean of 2.6452 and standard deviation of 0.6031. This indicates that documentation of results was not a challenge when it comes to the use of electronic device.

Table 1: General characteristics of study participants.


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Table 2: The respondents’ responses on challenges faced by personnel.


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From Figure 1, almost all the respondents agreed to the fact that results produced by electronic device are reliable as indicated by 93.5% (58) out of the total sample. Only 6.5% (4) of the respondents said results produced by electronic equipment are not reliable. The average duration most of these electronic devices produce result is in minutes as given by the respondents (77.4%, 48). Again, 6.5% (4) of the respondents however said the equipment produce results in hours. Finally, 16.1% (10) of the respondents said electronic equipment produced results in seconds (Figure 2). Table 3 presents mean score, standard deviation and percent frequencies on the respondents ‘attitude in the use of electronic services’ attitude scale. The mean scores of the respondent’s ranges between 3.3871 and 4.7097 while the standard deviations range between 0.45762 and 1.42983. Most of the mean scores items were above 4 (i.e. high agreement of the respondents) such as; “the use of these electronic device is helpful” with a mean score of 4.6774; “I work faster with these electronic device” had a mean score of 4.7097 and “electronic devices are user friendly” had a mean score of 4.3548. Percentages of most of the items were also very high in agreement. However, in two of the items thus “I have difficulty in working when these electronic devices break down’’ and “I have alternative means of working when these electronic devices break down”, percentage of the respondents who disagreed were 32.2% and 25.8% respectively. This indicates a number of the respondents were not in agreement to the development of positive attitude towards medical laboratory practice.

Figure 1: The respondents’ responses on the reliability of electronic service/device.


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Figure 2: The respondents’ responses on the duration electronic devices produce result.


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Table 3: The respondents’ responses on the impact of modern technology.


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This study examined the challenges medical laboratory personnel face in the use of electronic services and devices and its impact on the attitude of medical laboratory personnel. Majority of the respondents in this study showed positive attitude towards the operation of electronic devices understanding principle under which electronic devices work. However, the supply of electronic device accessories such as reagent was a major challenge. This is in line with the work of [4], which reported that the use of modern technology in the laboratory demanded high capital cost in terms of instrument installation and maintenance. According to his study, the status of international market may affect the supply of reagents and spare parts of equipment. Finally, the availability of maintenance of instruments and supply of reagent kits is limited to ‘big’ cities and not available in remote areas. A little over a quarter (27.4%) of our respondents agreed that calibration of electronic devices was easy, and therefore revealed negative response, with about 15% responding that maintenance/servicing of electronic device was easy. This indicates that a significant number of the respondents have challenges in using electronic device when there is the need to either maintain or service them. With the documentation of result by electronic equipment as a challenge, most of the respondents scored 3 with a mean of 2.6452 and standard deviation of 0.6031. This indicates that documentation of results was not a challenge when it comes to the use of electronic devices. It is in this direction that the study sought to identify some of the challenge’s medical laboratory personnel face in the use of electronic service and device and put in measures to help address these challenges. A higher proportion of the respondents agreed to the fact that results produced by electronic devices are reliable, with average duration of production being minutes indicating a better turnaround time. The study also revealed that the use of electronic device in the medical laboratory has had a positive impact on the attitude of some medical laboratory personnel. The mean score for most of the sub-scale was above 4 indicating positive attitudes. The implication is that some medical laboratory personnel have acquired some positive attitudes toward the practice of their profession after the introduction of electronic service and device in medical laboratories.

This is not surprising, since most of the laboratories are now moving from the manual way of practicing to the use of electronic services. The above findings are in line with [7], who confirmed technology makes use of laboratory equipment more user friendly, and also give better control of the entire process affecting the attitude of personnel positively. Again, [8] also reported that other benefits of electronic services in medical laboratories in relation to attitude of personnel include; decrease in the turnaround time (TAT) for the investigations. According to Markin and [9], in order to obtain high throughput, proper documentation, efficacy and accuracy with minimum expenditure of reagents in limited time and space, use of technology in the medical laboratory becomes very important. However, the use of electronic services and device in the laboratory also had some negative impact on the attitude of personnel. The mean score for two of the sub-scale was below 4 indicating negative attitudes. [4] reiterated that in cases of breakdown or if the equipment is out of order, alternative arrangements are very costly, and personnel often do not care leaving patients stranded. This was similar to the findings in our study, thus often alternative means of working when modern technology equipment break down are not there.In summary, the introduction of the electronic services has helped develop positive attitude in some medical laboratory personnel towards the practice of their profession[10].

Medical laboratory personnel had challenges with the supply of electronic device accessories such as reagent, calibration and maintenance/servicing of electronic device [11]. This requires immediate attention by authorities and other stake holders including the Ministry of Health and its agencies to address these challenges. Some personnel have developed positive attitude towards their work in the medical laboratory due to the introduction of electronic services and devices with each of the personnel receiving training before the use of electronic devices [12].

Based on the findings of the study, the following recommendations are made:

Reliable suppliers of electronic medical laboratory device and accessory must be engaged by hospital management such that supply of accessories such as reagent and others could be done quarterly. This must be done in order to avoid shortage in supply since most hospitals have policies which allow procurements to be done quarterly. Medical laboratory training institutions could collaborate with electronic medical laboratories for their students to have attachment and training on electronic medical laboratory services such that before the student’s complete school they are adequately prepared for electronic services in the various medical laboratories. The ministry of health must encourage all medical laboratories in Ghana to use electronic services since its use will have a positive impact on the attitude of personnel towards the practice of their profession. There must be workshops and refresher courses for medical laboratory personnel on the use of electronic services and devices by the Allied Health Professions Council of Ghana on regular basis so personnel could abreast themselves with current trends in the use of electronic services and devices in medical laboratories.

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