Evaluation of the Anti-Inflammatory Activity of Semi-Purified Glycoside Extracted from the Leaves of Plumeriarubra (Kalachuchi) by Renato I Dalmacio in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers
The researchers focused on skin inflammation. An inflammation is a biological response of the body aiming to remove the harmful stimuli that affects a part of our body. Based on visual observation, the ancients characterized inflammation by five cardinal signs; heat (calor) is caused by the increased movement of blood through dilated vessels into the environmentally cooled extremities, also resulting on the increased redness (rubor), swelling (tumor) is the result of increased passage of fluid from dilated and permeable blood vessels into the surrounding tissues, infiltration of cells into the damaged area, and in prolonged inflammatory responses deposition of connective tissue, pain (dolor) is due to the direct effects of mediators, either from initial damage or that resulting from the inflammatory response itself, and the stretching of sensory nerves due to oedema and loss of function (functiolaesa) refers to either simple loss of mobility in a joint. (Punchard N.A., Whelan C.J., Adcock I., 2004)[1-3].
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