To Examine the Relationship and Strength of Alcohol- Related Intimate Partner Violence in sub-Saharan Africa (RRHOAJ)-Lupine Publishers

To Examine the Relationship and Strength of Alcohol- Related Intimate Partner Violence in sub-Saharan Africa by Ekpenyong MS in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

Alcohol-related intimate partner violence (IPV) is a serious public health issue which has attracted a lot of research and debates. While some studies have reported the relationship between alcohol and IPV to be linear, others have reported threshold effects. While some studies have found the link to be strong, others have reported weak or no association. Using Logistic regression and meta-analysis, the relationship, strength of relationship and possible moderators of the alcohol-IPV link are investigated in ten sub-Saharan African countries. The results indicates that while alcohol consumption is associated with IPV in three of the countries, alcohol abuse was associated with IPV in the other seven countries lending support for both the linear and threshold effects in sub-Saharan Africa. The meta-analysis showed a strong association between alcohol and physical IPV while a weaker association was observed for the alcohol- sexual IPV link. Moderator analysis showed that the strength of the alcohol-IPV link in sub-Saharan Africa varies with wealth index, marital length, and marital status, and jealousy, place of residence and justification of the use of violence. The nature of moderation was different between countries. The results of this study can be applied to plan country specific and multi-faceted intervention programs.

https://www.lupinepublishers.com/research-and-reviews-journal/abstracts/to-examine-the-relationship-and-strength-of-alcoholrelated-intimate-partner-violence-in-sub-saharan-africa.ID.000110.php

https://www.lupinepublishers.com/research-and-reviews-journal/pdf/RRHOAJ.MS.ID.000110.pdf

https://www.lupinepublishers.com/research-and-reviews-journal/fulltext/to-examine-the-relationship-and-strength-of-alcoholrelated-intimate-partner-violence-in-sub-saharan-africa.ID.000110.php

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Immunogeneicity of Recombinant Therapeutic Interferon Alpha(RRHOAJ)-LupinePublishers

Immunogeneicity of Recombinant Therapeutic Interferon Alpha by  Hafiza Rida Farooq Chudhary in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

Therapeutic recombinant interferons and cytokines are being used to treat different diseases but these proteins can start immunogenic reactions. These reactions neutralize the effect of therapeutic proteins and make them useless. There are many factors responsible for causing and effecting immunogenicity including dosage, route of administration, genetic status, and polymorphism and Allergic responses. The body's first immune response against recombinant therapeutic cytokines is mediated by innate system, subsequently activating the adaptive immune system. The key factors in immunogenicity are the glycosylation and aggregated structure of therapeutic protein that distinguishes the protein/cytokine from self-proteins. There are many ways to reduce immunogenicity like to decrease the number of epitopes for T-cells or by screening the history of allergies. IFNs are basically proteins in nature many of which are related both in 3D structure and amino acid sequences. Recombinant Interferons are widely used these days against viral infections and cancers. In this review the antiproliferative activity and the effects of various recombinant human interferons on the cytotoxic and cytostatic activity of natural killer cells and monocytes are discussed in detail.

https://lupinepublishers.com/research-and-reviews-journal/abstracts/immunogeneicity-of-recombinant-therapeutic-interferon-alpha.ID.000112.php 

https://lupinepublishers.com/research-and-reviews-journal/pdf/RRHOAJ.MS.ID.000112.pdf 

https://lupinepublishers.com/research-and-reviews-journal/fulltext/immunogeneicity-of-recombinant-therapeutic-interferon-alpha.ID.000112.php 

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Gender difference in learning disabled children Neuropsychological review(RRHOAJ)-Lupine Publishers

Gender difference in learning disabled children Neuropsychological review by  Mohamad Qasim Abdullah in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

This review aimed to investigate the gender differences in learning disabilities among children. It is highlighted the nature of learning disabilities, and reviewed the gender differences on one hand, and explanation of theoretical background on the other hand. Finally, it is centred on the neuropsychology of these complicated behavioral phenomena. The conclusion of this article is that we are in the midst of investigating differences between male and female from multidimensional and methodological approaches because there are some critical issues regarding the assessing this complicated behavioural phenomena.

https://lupinepublishers.com/research-and-reviews-journal/abstracts/gender-difference-in-learning-disabled-children-neuropsychological-review.ID.000111.php 

https://lupinepublishers.com/research-and-reviews-journal/pdf/RRHOAJ.MS.ID.000111.pdf

https://lupinepublishers.com/research-and-reviews-journal/fulltext/gender-difference-in-learning-disabled-children-neuropsychological-review.ID.000111.php

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Circadian Disruption, Sleep Loss, and Low-Grade Inflammation(RRHOAJ)-Lupine publishers

Circadian Disruption, Sleep Loss, and Low-Grade Inflammation by Rüdiger Hardeland in Research and Reviews on Healthcare: Open Access Journal in Lupine publishers

Circadian rhythmicity is a fundamental property of the majority of organisms, including bacteria, unicellular eukaryotes, fungi, plants and animals. It is generated by cellular oscillators and may have evolved to cope with adverse phases in the cycle of a day that bear the risk of damage by radiation and reactive metabolites, such as free radicals. In a complex organism like the human, the circadian system is composed of numerous, internally communicating, oscillators including a coordinating master clock, the suprachiasmatic nucleus (SCN) . It provides a program for structuring countless physiological functions in a sophisticated temporal pattern that optimizes the alignment of processes and also the anticipation of regularly expectable changes, such as an approaching time of arousal and locomotor activity, of food intake and even social interactions.

https://www.lupinepublishers.com/research-and-reviews-journal/abstracts/circadian-disruption-sleep-loss-and-low-grade-inflammation.ID.000109.php

https://www.lupinepublishers.com/research-and-reviews-journal/pdf/RRHOAJ.MS.ID.000109.pdf

https://www.lupinepublishers.com/research-and-reviews-journal/fulltext/circadian-disruption-sleep-loss-and-low-grade-inflammation.ID.000109.php

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Nanoemulgel Innovative Approach for Topical Gel Based Formulation(RRHOAJ)-Lupine Publishers

Nanoemulgel Innovative Approach for Topical Gel Based Formulation by Bhupendra G Prajapati in Research and Reviews on Healthcare: Open Access Journal in Lupine Publishers

The lipophilic nature of majority of newly developed drugs has resulting in poor bioavailability, and pharmacokinetic variations. The goal of this evaluation is to evaluate and report the current potential and future scope of nanoemulgel formulation for becoming an effective delivery system for poorly water-soluble drugs. Nanoemulgel consist two different systems in which drug containing nanoemulsionis incorporated into a gel base. The fusion of these two systems makes this formulation advantageous in several ways. Lipophilic drugs can be easily incorporated and the skin permeability of the incorporated drugs can be enhanced in several folds due to the finely distributed oil droplets in gel phase. Simultaneously, it can be targeted more specifically to the site of action and can avoid first pass metabolism and relieve the user from gastric/systemic incompatibilities. The nanoemulgel drug delivery system is a formulation related intervention to improve drug absorption and therapeutic profile of lipophilic drugs. An increasing trend in nanoemulgel use in recent years has been noticed because of the better acceptability of the preparation to the patients due to their non-greasy, convenience spreadability, and easy applicability and good therapeutic and safety profile. Despite having few limitations, nanoemulgel formulation can be considered as potential and promising candidates for topical delivery of lipophilic drugs in the future.

https://www.lupinepublishers.com/research-and-reviews-journal/abstracts/nanoemulgel-innovative-approach-for-topical-gel-based-formulation.ID.000107.php

https://www.lupinepublishers.com/research-and-reviews-journal/pdf/RRHOAJ.MS.ID.000107.pdf 

https://www.lupinepublishers.com/research-and-reviews-journal/fulltext/nanoemulgel-innovative-approach-for-topical-gel-based-formulation.ID.000107.php

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